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Health

Category: Health

  • Herb Spoke To Parents Treating Their Children With CBD

    Herb Spoke To Parents Treating Their Children With CBD


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    Autism spectrum disorder affects one in 68 American children, but what’s the relationship between CBD and autism? Parents treating children with CBD?

    Although there are currently no published studies on the subject, there is tons of anecdotal evidence that says CBD and autism is a good fit, especially considering how strong the prescription alternative can be. We did the research and spoke with mothers of children with autism, to teach you how CBD and whole plant medicine can be an effective treatment for autism.


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    What is Autism?

    Autism is a developmental disorder that affects people’s ability to communicate and interact with others. It is known as a spectrum because it affects individuals in varying degrees. Some other behaviours that are common in autism spectrum disorder include delayed language, difficulty making eye contact and having a conversation, sensory sensitivities, intense interests, and repetitive behaviour. Because it’s a spectrum, folks with autism may display many or few of these signs – it depends on the individual.

    Autism is frequently accompanied by other medical issues, like gastrointestinal (GI) disorder, sleep disturbances, anxiety, phobias, ADHD, and OCD. But that’s the first place where CBD and autism link, many of those medical issues can be relieved by cannabis.

    What’s more, the inability to communicate can be very frustrating for those with autism. It can cause lead to other behaviours, like anxiety, rage, and self-harm, as well as body rocking and other repetitive self-soothing behaviours. But this is where CBD and autism meet again, because of cannabis’ anti-anxiety and calming effects.

    The Endocannabinoid System and Autism

    The Endocannabinoid system is where the CBD and autism connection really starts to make sense. A lot of autism’s symptoms are directly related to the functions of the body’s endocannabinoid system (ECS). The ECS is the largest regulatory system in the body and controls:

    • mood
    • pain
    • sleep
    • appetite
    • pleasure and reward
    • motor control
    • memory

    Plus, our bodies have endocannabinoid receptors in almost every cell. When a 2013 study found dysfunctions in cannabinoid receptors on immune cells in autistic children, it was an “aha” moment for CBD and autism researchers. Could supplementing autistic people with cannabis improve their symptoms?

    CBD and Autism

    Some parents, like Shifra Klein, would say yes. Her 12-year-old son was diagnosed with severe autism at age two and has been on over 13 medications to help control symptoms since.

    “Our son is almost completely weaned off of drugs [since beginning CBD treatment],” says Klein. “He is more focused in school, able to stay on task, understand and follow classroom multi-step directions, complete schoolwork, and is no longer at a ‘plateau’ and able to grasp new concepts. His eye contact is better, his language is more thought-out and he is able to create meaningful sentences and his annunciation is clearer. He also seems happier, in general.”

    CBD and autism have been a great fit for Klein’s son, but because there is practically no clinical evidence for its success, autism isn’t a qualifying condition for medical marijuana in most states. However, the anecdotal evidence is growing and has sparked the formation of activist groups like Mothers Advocating Medical Marijuana for Autism (MAMMA).

    Klein is an early education teacher as well as parent and so she understands the doubt, fear, and stigma parents experience when considering CBD and autism.

    “I still encourage other parents to use resources available to them, such as therapies, but this is such a wonderful addition and has really been effective for us,” says Klein.

    As far as dosing CBD goes, Klein warns it might be a bit of trial and error, but it will be well worth it. She also urges parents to make sure their CBD oil is from a reliable source and is tested by a third-party lab to ensure quality and safety.

    “I would never recommend anything to another child that I would not give to my own,” says Klein. “You will not harm your child by trying CBD to see if it works for them. You will not overmedicate your child with CBD.”

    The Problem with Other Medications

    CBD and autism come as a relief for parents because other drugs prescribed to children with autism are powerful. Often these kids are prescribed Abilify or Seroquel: anti-psychotics not specifically for autism, or children for that matter.

    “You won’t find even one single study that shows what happens to a very young child who’s treated lifelong with antipsychotics,” says Abigail Dar, mother of an autistic son, researcher, and advocate for cannabis for autism in Israel. “None of them [antipsychotic medications] have been targeted for children. I’m talking five [years old].”

    These antipsychotic drugs have tons of negative side effects, including dizziness, drowsiness, stomach pain, and weight gain. And yet, they are most doctor’s first choice for treating autism. However, many criticize them for being too strong and turning kids with social disabilities into zombies. Or, as Dar puts it: “You give it to children who can’t communicate how they feel.”

    Dar also pointed out another troubling dilemma with antipsychotic medications. One of their side effects includes lowering the seizure threshold, yet autistic children are at high risk for epilepsy; 30% of those with autism also have epilepsy. Dar’s son didn’t have epilepsy until he was 16 and she isn’t sure if it was caused by medications for the autism rather than the autism itself.

    “If he didn’t have epilepsy we may have triggered it,” says Dar. “I’m asking now, why did you give my son who’s already at risk for seizures [these drugs]?”

    Cannabis, on the other hand, is anecdotally more effective at treating symptoms and much less harmful. In fact, CBD oil without THC is non-psychoactive and has no side effects aside from possible drowsiness. CBD and autism is such a great match because children are more engaged whereas anti-psychotics leave them the opposite. Plus, hemp-derived CBD oil is available in all 50 states.

    CBD and autism have tons of potential. The anecdotal evidence is building and soon, we’ll have scientific evidence to back it up. For families looking for alternative treatment, CBD and autism might be the answer they were searching for.

    Reference Click Here

  • Everything You Need To Know About Using CBD

    Everything You Need To Know About Using CBD


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    The compound, found in the cannabis plant, is thought to be good for muscle pain, headaches and anxiety, among other things. But what does the research say?

    James Joliat, a 35-year-old video producer in Denver, has long experienced muscle and joint pain—mostly related to sports injuries. He says he started looking at natural remedies as an alternative to the prescription patches and pills his doctor recommended. After experimenting with homemade rubs infused with plant compounds—stuff like arnica and turmeric—he eventually stumbled onto topical cannabidiol (CBD) rubs.

    “I put that on my ankle after hiking or on my lower back, and it just feels like it really penetrates and has good anti-inflammatory properties,” he says. “I also fucked up my shoulder, and I felt like it helped a lot with the pain.”

    He’s been using topical CBD for years with good results, and he recently tried ingesting CBD oil, which he called an “amazing” experience. “I just felt super relaxed—kind of an anti-anxiety type of feeling,” he says. “My body felt super mellow and limber, but not in a tired kind of way.”

    “I just felt good,” he adds. “But I wasn’t high at all.” Joliat’s anecdotal experience with CBD is a common one. Some informal polling suggests a lot of people today are at least vaguely familiar with cannabidiol and have either used it themselves or know someone who has. But even some people who use it don’t seem to know exactly what it is or whether there’s any hard science out there to back up its benefits.

    What Is CBD?

    “Cannabidiol is a compound found in the cannabis plant,” says Jerzy Szaflarski, a professor of neurology and director of the Division of Epilepsy at the University of Alabama, Birmingham.

    Szaflarski explains that cannabis contains about 500 different compounds, some of which—including CBD and THC—interact with certain chemical receptors in the human nervous system. But unlike THC, CBD isn’t psychoactive—meaning it doesn’t cause any kind of a high. Despite that, the US Drug Enforcement Agency classifies CBD (and other cannabis compounds) as schedule I substances, making their sale illegal in many states.

    “The brain has these receptors that respond to endocannabinoids, which are neurotransmitters that are naturally produced in the body and brain,” says Jerald Simmons, a neurologist at Houston’s Comprehensive Sleep Medicine Associates. “Some of the cannabinoids in the marijuana plant are very similar to the endocannabinoids in the brain, and they act on the same receptors.”

    The nervous system’s endocannabinoid system is not well understood. But it’s thought to play a role in regulating pain, sleep, mood, memory, appetite, and other cognitive and physical processes. Because CBD is able to mimic the actions of some natural brain chemicals, its potential therapeutic benefits are wide-ranging but—at this point—nebulous. “We know that cannabidiol modulates the endocannabinoid system, but we don’t know how it works,” Szaflarski says. That said, there are theories.

    “THC”—the more-famous, high-inducing compound in cannabis—“works directly on the cannabinoid system, meaning it attaches to receptors and mimics some of our own internal endocannabinoids,” says Igor Grant, a professor and chair of psychiatry at the University of California, San Diego School of Medicine. But CBD’s interaction with the endocannabinoid system is subtler. “Normally, these endocannabinoid-signaling molecules are broken down by enzymes, and one thing CBD does is interfere with the actions of those enzymes.”

    Grant says this may lead to a “dampening” or mellowing of some neurochemical processes, including those linked to pain. “CBD may also react with other receptors, like those for serotonin, and it may have actions that reduce the inflammatory molecules produced whenever there is tissue damage or bacteria coming in,” he says. “But we really don’t know the mechanisms.”

    Should I take CBD to treat pain?

    Talk to people or spend time on internet message boards, and you’ll see CBD is thought to have anti-pain, anti-soreness, and anti-inflammatory benefits. Some rat studies have linked topical CBD treatments to a drop in arthritis-related pain and swelling, and more research suggests it could help relieve headaches.

    That headache study cites research linking CBD to lower rates of anxiety. (Since anxiety often produces headaches, the authors say, CBD could be a plausible headache remedy if those anti-anxiety benefits are legit.) Grant says he’s looked at the literature on CBD and anxiety, and some of it is enticing. He mentions a Brazilian study, for instance, that found people with a fear of public speaking felt less anxiety and less discomfort about their phobia after taking CBD, compared to those who took a placebo.

    “There’s also some evidence it reduces psychotic symptoms in people with schizophrenia and psychotic disorders,” Grant says. “But there are a lot of open questions at this point.”

    One area where CBD is clearly helpful: the treatment of seizures associated with one form of epilepsy. A 2017 New England Journal of Medicine study found ingesting oral CBD dramatically cut down most patients’ seizure frequency—a finding that prompted the FDA to support the approval of one CBD drug for use in the treatment of some epilepsy patients.

    How do people take CBD?

    It’s usually sold as a droplet-administered oil or a balm, but it’s also sold in caplets, under-the-tongue tabs, lotions, face serums, and other products.

    Some users speculate about appropriate dosages or methods of application—including whether or not a small amount of THC boosts CBD’s effects, or whether different methods of administration lead to quicker or more significant effects. Some CBD producers also claim that it has a cumulative effect, and so needs to be used regularly to produce a benefit. But Grant says it’s tough to say at this point exactly how people should (or shouldn’t) be using CBD.

    “Even where marijuana is legal, you often don’t know exactly what you’re getting,” he says. “I’m sure some of these [CBD] producers have labs and do correct labelling, but none of it’s secure like it is with pharmaceuticals.”

    The nutrition and supplement industry—which includes CBD products—is almost wholly unregulated. “The concentrations in products are only approximate, and I don’t know how well they’re tracked,” Szaflarski says. Even if you could absolutely trust a product’s label—and many CBD manufacturers, aware of the current scrutiny on their industry, go to great lengths to assure consumers of the quality of their products—there aren’t a lot of concrete facts when it comes to the type or amount of CBD a person should take for a specific ailment or aim.

    Are there any risks to taking CBD?

    Some studies have turned up evidence—nearly all of it from lab work or animal research—that CBD could potentially affect cell health, fertility, and the breakdown and metabolism of drugs in the liver. “There may be some interactions with pharmaceutical drugs,” Szaflarski says, mentioning drowsiness as one (but not the only) possibility.

    In human studies, including one that found anti-seizure benefits among epileptics, some people have reported diarrhoea, vomiting, fever, and fatigue while taking CBD.

    “But so far, the main risks are that it does seem to have a sedative action, so people could get drowsy,” Grant says. “I have not read about major side effects or bad reactions, so it seems relatively safe as far as we know, but we need systematic research on this.”

    While there are more unknowns than knowns at this point, Grant says he doesn’t discount all the anecdotal CBD reports. “You hear somebody say, ‘Hey, I gave this to myself and my kid and we feel a lot better,’ and we should never dismiss that kind of information,” he says. He points out that many modern medicines were discovered when researchers followed up on exactly this sort of human trial-and-error evidence. “But we still need to do the studies that confirm whether all the good things are true, and how much to give, and how to give it,” he says. “These are all questions that need to be answered.”

    Reference: Vice

  • The Hemp Revival: Why Marijuana’s Cousin Could Soon Be Big Business

    The Hemp Revival: Why Marijuana’s Cousin Could Soon Be Big Business


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    The useful crop has seen renewed interest alongside legalized weed with US officials warming to it

    Long associated with the hoariest hippie stereotypes, hemp (CBD) is now chic.
    The crop – which is a cannabis plant very similar to marijuana, but lacking its best-known property: getting you high – is a versatile raw material, and like its more notorious relative, it could once again become very lucrative.

    The spread of marijuana legalization has sparked renewed interest not because of hemp wallet fanatics – but due largely to demand for CBD, a chemical both it and marijuana produce in which some see potential as a pharmaceutical and nutritional supplement.

    For decades US anti-marijuana laws have made it very difficult to experiment on and develop new uses for hemp, though, according to the US government, hemp contains less than 0.3% THC, the plant’s primary psychoactive ingredient.

    But the climate is changing. In recent weeks, the US Senate majority leader, Mitch McConnell, a conservative Republican who opposes marijuana legalization, has called for hemp to be legalized, a move which would benefit farmers, though McConnell still opposes marijuana legalization.

    And it’s not just the farmers in McConnell’s home state of Kentucky who would be pleased to see a resurgence of the crop. Early this month for hemp history week, the US Senate unanimously passed a non-binding resolution acknowledging hemp’s economic value and “historical relevance”.

    China, though wary of marijuana, has emerged as a hemp “superpower”, according to a fascinating 2017 story in the South China Morning Post. While hemp is indigenous to China, Chinese research advanced only recently in 1970 when the military used it for uniforms that would be more comfortable in the Vietnamese jungle. Today, the Morning Post notes, China holds more than half of the world’s more than 600 hemp-related patents.

    Hemp’s revival is only the latest chapter in a long history.

    In China, hemp has been used to make fabric and rope for more than 3,000 years. A Chinese eunuch named Cai Lun, who is credited with inventing paper during the early Christian era, used hemp as one of his source materials.

    Between the 16th and 18th centuries, hemp rope, sails and rigging were so vital to the British Royal Navy that the supply was considered a national security issue. Both Henry VIII and Elizabeth I encouraged growing the crop.

    In the US, some of the founding fathers grew hemp. Stoner lore has it that the constitution and declaration of independence were written on hemp. It’s not true – they were written on parchment – but drafts of the documents probably were.

    But interest in hemp waned as cotton, a finer fabric dependent on American slave labor, ascended. It was last a relevant crop in the US during the second world war, when the Department of Agriculture made a Hemp for Victory film and encouraged production.

    Today’s hemp advocates, a passionate cohort indeed, claim paper, cloth and biofuel made from hemp are all environmentally and economically attractive, relative to the prevailing current methods. If hemp became a major source for any one of these staples, it would be an immense opportunity, akin to legal marijuana.

    And there are more uses for hemp still. The seeds are a good source of protein, popular with vegans. Hemp can also be made into a building material known as hempcrete, which is currently easier to access in parts of Europe than in the US. A bridge in sixth-century Gaul was built from hempcrete.

    Bryan DeHaven’s Colorado-based clothing company, Chiefton Supply Co, makes T-shirts from a hemp/cotton blend. The component organic hemp is grown, processed into fabric and then stitched into apparel all at one facility in China’s Shangdong province.

    DeHaven said hemp’s benefits included that it needed substantially less water than cotton to grow. The resultant cloth, he said, also had anti-bacterial properties; Chiefton is working with sportswear companies on breathable hemp clothing for athletes. “Those guys are really putting our garments to the test,” he said.

    Eventually, DeHaven said, he would like to see Chiefton hemp goods produced in the US “from seed to seam”. It will be difficult. Hemp is not completely illegal in the US but the current rules are wildly convoluted, probably even more so than those for marijuana.

    But the laws weren’t the main problem, DeHaven said. You can’t make hemp clothing in the US because the country no longer has sufficient expertise in textile production.

    Reference: The Guardian

  • What Is CBD? The ‘Miracle’ Cannabis Compound That Doesn’t Get You High

    What Is CBD? The ‘Miracle’ Cannabis Compound That Doesn’t Get You High


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    The cannabis-derived chemical is non-psychoactive and has been hailed as a cure for the disease in early May.

    A federal court declined to protect cannabidiol (CBD), a chemical produced by the cannabis plant, from federal law enforcement, despite widespread belief in its medical value.

    The ruling was contrary to existing evidence, which suggests the chemical is safe and could have multiple important uses as medicine. Many cannabis advocates consider it a miracle medicine, capable of relieving conditions as disparate as depression, arthritis and diabetes.

    The perception of its widespread medical benefits has made the chemical a rallying cry for legalization advocates.

    The first thing to know about CBD is that it is not psychoactive; it doesn’t get people high. The primary psychoactive ingredient in marijuana is tetrahydrocannabinol (THC). But THC is only one of the scores of chemicals – known as cannabinoids – produced by the cannabis plant.

    So far, CBD is the most promising compound from both a marketing and a medical perspective. Many users believe it helps them relax, despite it not being psychoactive, and some believe regular doses help stave off Alzheimer’s and heart disease.

    Experts: medical marijuana (Cannabis) draws parents to US for their children’s treatments

    While studies have shown CBD to have anti-inflammatory, anti-pain and anti-psychotic properties, it has seen only minimal testing in human clinical trials, where scientists determine what a drug does, how much patients should take, its side effects and so on.

    Despite the government ruling, CBD is widely available over the counter in dispensaries in states where marijuana is legal.

    CBD first came to public attention in a 2013 CNN documentary called Weed. The piece, reported by Dr Sanjay Gupta, featured a little girl in Colorado named Charlotte, who had a rare life-threatening form of epilepsy called Dravet syndrome.

    At age five, Charlotte suffered 300 grand mal seizures a week and was constantly on the brink of a medical emergency. Through online research, Charlotte’s desperate parents heard of treating Dravet with CBD. It was controversial to pursue medical marijuana for such a young patient, but when they gave Charlotte oil extracted from high-CBD cannabis, her seizures stopped almost completely. In honour of her progress, high-CBD cannabis is sometimes known as Charlotte’s Web.

    After Charlotte’s story got out, hundreds of families relocated to Colorado where they could procure CBD for their children, though not all experienced such life-changing results. Instead of moving, other families obtained CBD oil through illegal distribution networks.

    In late June, the US Food and Drug Administration could approve the Epidiolex, a pharmaceutical form of CBD for several severe pediatric seizure disorders. According to data recently published in the New England Journal of Medicine, the drug can reduce seizures by more than 40%. If Epidiolex wins approval it would be the first time the agency approves a drug derived from the marijuana plant. (The FDA has approved synthetic THC to treat chemotherapy-related nausea.)

    Epidiolex was developed by the London-based GW Pharmaceuticals, which grows cannabis on tightly controlled farms in the UK. It embarked on the Epidiolex project in 2013, as anecdotes of CBD’s value as an epilepsy drug began emerging from the US.

    While parents treating their children with CBD had to proceed based on trial and error, like folk medicine, they also had to wonder whether dispensary purchased CBD was professionally manufactured and contained what the package said it did. GW brought a scientific understanding and pharmaceutical-grade manufacturing to this promising compound.

    Fortunately, like THC, CBD appears to be well tolerated; as far as I can tell, there are no recorded incidents of fatal CBD overdoses.

    Since Weed first aired, GW’s stock has climbed 1,500%.

    Should I grow my own weed at home? Here’s what you need to know

    GW’s first drug Sativex, which contains both CBD and THC, is available as a treatment for MS-related spasticity in Canada, Australia, and much of Europe and Latin America. The company is also studying cannabinoid-based drugs as a treatment for autism spectrum disorders, an aggressive brain tumour called glioblastoma, and schizophrenia.

    Other industries, not subject to the strict regulations governing pharmaceuticals are eager to develop their own CBD products, everything from joints and vape pens to skin creams and edibles which may or may not have a valid medical use.

    In Los Angeles, it’s among the latest wellness fads. It can be found in cocktails, and an upscale juice shop will even add a few drops of CBD infused olive oil to a beverage for $3.50.

    Reference: The Guardian


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