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pain

Tag: pain

  • The True Benefits Of Taking CBD Oil

    The True Benefits Of Taking CBD Oil


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    Cannabidiol (CBD) is a compound in the cannabis plant which has already made a name for itself, and its merits are extolled by more and more people around the world. Cannabidiol is also known as the compound which doesn’t have the psychoactive effects found in another compound, THC, and it has proven itself as a great supplement for people who suffer from various ailments and has been believed to help with pain and sleep. But if you are keen on finding out more about CBD oil and what it can actually do, it does pay to do research about the compound and its effects. So what do you need to know about the true benefits and advantages of taking CBD oil? Let’s find out.


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    What it is – and how it is made

    While tetrahydrocannabinol, or THC, is the compound in the marijuana plant which is associated with that ‘high’ or ‘stoned’  feeling, CBD doesn’t have quite the same effect. As mentioned, cannabidiol is not psychoactive, and this makes it the ideal solution or option for those who are not interested in getting that ‘high’ effect but who would like to find relief from pain or other ailments. CBD oil is produced with the extraction of the compound from the plant, and it is then diluted or mixed with an oil such as hemp seed or coconut oil in order to produce CBD oil.

    The potential benefits and advantages of CBD oil

    • Pain

    Did you know that the marijuana plant has been utilised for centuries for pain? In recent times, scientists have found that certain marijuana plant components, such as CBD, may be responsible for pain relief. This is because the body has an endocannabinoid system, or ECS, which is associated with the regulation of functions that include sleep, pain, immune system responses, and appetite. The human body can produce endocannabinoids, and these are neurotransmitters which bind to the cannabinoid receptors in a person’s nervous system. In certain studies, it was found that CBD oil may potentially reduce pain by having an impact on the activity of endocannabinoid receptors, which, in turn, may reduce inflammation and interact with the body’s neurotransmitters.

    CBD oil is now extensively used for the treatment of various conditions, and individuals believe that it is quite effective in the treatment of acne and other more serious conditions. Whilst they still need to do further studies on the real effects of CBD on peoples’ health and conditions, this natural supplement is definitely worth a try.

     

    Sources:

    https://www.ncbi.nlm.nih.gov/

  • Athletes Are Choosing CBD For Their Recovery

    Athletes Are Choosing CBD For Their Recovery


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    Andrew Talansky is almost always sore. The 29-year-old spent seven years as a professional cyclist racing for Slipstream Sports. He recently switched to triathlon and now spends hours training both on and off the bike. “I’m using muscles I haven’t used in years,” Talansky says. “My body is constantly inflamed.” Many athletes in his situation rely on common pain relief like ibuprofen, but when Talansky strained a hip flexor last fall, he reached for a bottle of cannabidiol (CBD), an extract from the cannabis plant, choosing CBD instead.

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    “I took it for a couple of weeks, and there was a noticeable difference immediately,” Talansky says. “And it wasn’t just that my hip was feeling better. I was less anxious, and I was sleeping better.”

    Marijuana has long been considered an alternative pain medication, with THC, the principle psychoactive compound in the plant, getting most of the attention. CBD is another active component and could offer some of the same medical benefits (anti-inflammatory, anti-anxiety, analgesic), but without the side effect of getting high. CBD interacts with serotonin and vanilloid receptors in the brain, which affect mood and the perception of pain. It also has antioxidant properties. The World Anti-Doping Agency (WADA) removed CBD from its list of banned substances in January, which prompted many professional athletes, including ultrarunner Avery Collins and mountain biker Teal Stetson-Lee, to eschew ibuprofen for CBD. Some believe it’s a safer alternative to drugstore pain relievers and anti-inflammatories.

    More than a dozen countries have CBD-based medications on the market, including Canada and Israel, but in the U.S. advanced clinical trials are still in their infancy.

    Research on CBD has been slow to accumulate, largely because the federal government considers marijuana a Schedule I drug—the same classification given to heroin and LSD—making it difficult for researchers to gain access to it for study. And because many states have already legalized the drug for medical use, pharmaceutical companies have little incentive to conduct costly clinical trials demonstrating its efficacy. (CBD remains illegal in several states that have yet to pass medical-marijuana or CBD exemptions.)

    Still, the market for CBD is booming. According to a study by the Brightfield Group, a market-research firm based in Tampa, Florida, hemp CBD generated $170 million in revenue in 2016. With annual sales growing at a rate of 55 percent, it’s poised to be a $1 billion industry by 2020. Charlotte’s Web, which bottles the extract in Colorado, is one of the largest producers in the industry. Talansky’s CBD of choice comes from Floyd’s of Leadville, also in Colorado, which was launched in 2016 by former pro cyclist Floyd Landis. Floyd’s of Leadville markets its products directly to athletes looking for a natural recovery supplement. “Think of your 40-year-old endurance athlete who wants to feel good when he wakes up in the morning,” Landis says. “That’s our target.”

    Landis uses CBD to manage pain from a hip replacement he had in 2006. He relied on WADA-approved opioid-based painkillers for years, both before and after he was stripped of his 2006 Tour de France victory for using synthetic testosterone. Eventually, Landis leaned on pot smoking to kick his opioid habit, and in 2015 a friend in the burgeoning marijuana industry suggested Landis try CBD instead.

    “It’s the only thing I use now,” Landis says. “I try not to oversell it, because I don’t want to sound insane. But if you can stop taking other pain medications, if you have a natural solution, that’s probably the better option.”

    There is research to back up his enthusiasm. A 2008 review by GW Pharmaceuticals examined two decades’ worth of preclinical studies and animal trials before concluding that CBD can be a successful tool for pain management without many adverse side effects. A 2016 study by the University of Kentucky examined CBD’s effects on arthritic rats and found that the compound reduced inflammation and overall pain. Some studies have also labelled it a neuroprotectant, suggesting that it has the ability to bolster the brain against the damaging effects of concussion. More than a dozen countries have CBD-based medications on the market, including Canada and Israel, but in the U.S. advanced clinical trials are still in their infancy.

    “There is overwhelming evidence that CBD can be effective for mitigating pain,” says Jahan Marcu, chief science officer with Americans for Safe Access, which works to legalize medical marijuana. “But we haven’t seen the full clinical trials necessary to understand exactly how it works.”

    Prospective CBD users should keep in mind that the scientific community still has a lot to learn about the drug. For instance, there have been no studies on the recommended dosage for a given ailment. There’s also no scientific consensus about how effective CBD is compared with anti-inflammatories like ibuprofen or naproxen. That could change soon: at least 20 clinical trials examining the medical benefits of CBD are currently underway in the U.S., including a $16 million effort by the University of Miami, which is looking into CBD’s effects on brain trauma.

    Beyond these questions, there’s also growing concern about the quality of the products currently for sale. Because the federal government considers CBD an illegal drug, the industry is underregulated by the FDA, with little third-party oversight. A 2017 study published in The Journal of the American Medical Association found that 69 percent of the CBD products tested didn’t contain the amount of cannabidiol indicated on the label. Most CBD companies don’t sell through retail outlets; they reach consumers online.

    “You can’t really trust what you’re buying over the Internet,” says Ryan Vandrey, who researches cannabis at Johns Hopkins University and coauthored the 2017 JAMA study. “After purchasing every CBD oil you could buy, we found that a number of companies were selling products that contained almost no cannabidiol, and others contained THC.”

    While there are many unknowns, anecdotal and preclinical evidence for the efficacy of CBD continues to build. Vandrey is conducting an ongoing survey of more than 1,000 users of marijuana products, many of them with CBD, and his initial findings suggest that the majority have seen an overall improvement in terms of pain relief, sleep satisfaction, and anxiety reduction, though the cause remains unclear. And a growing number of athletes like Talansky believe that aiding recovery without the long-term side effects of ibuprofen (such as the increased risk of heart failure) or the addictive qualities of opioids is a step in the right direction. “I haven’t taken an Advil in months,” Talansky says. “For any athlete who trains hard, that’s saying a lot.”

    Referece:outsideonline.com

  • Herb Spoke To Parents Treating Their Children With CBD

    Herb Spoke To Parents Treating Their Children With CBD


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    Autism spectrum disorder affects one in 68 American children, but what’s the relationship between CBD and autism? Parents treating children with CBD?

    Although there are currently no published studies on the subject, there is tons of anecdotal evidence that says CBD and autism is a good fit, especially considering how strong the prescription alternative can be. We did the research and spoke with mothers of children with autism, to teach you how CBD and whole plant medicine can be an effective treatment for autism.

    What is Autism?

    Autism is a developmental disorder that affects people’s ability to communicate and interact with others. It is known as a spectrum because it affects individuals in varying degrees. Some other behaviours that are common in autism spectrum disorder include delayed language, difficulty making eye contact and having a conversation, sensory sensitivities, intense interests, and repetitive behaviour. Because it’s a spectrum, folks with autism may display many or few of these signs – it depends on the individual.

    Autism is frequently accompanied by other medical issues, like gastrointestinal (GI) disorder, sleep disturbances, anxiety, phobias, ADHD, and OCD. But that’s the first place where CBD and autism link, many of those medical issues can be relieved by cannabis.

    What’s more, the inability to communicate can be very frustrating for those with autism. It can cause lead to other behaviours, like anxiety, rage, and self-harm, as well as body rocking and other repetitive self-soothing behaviours. But this is where CBD and autism meet again, because of cannabis’ anti-anxiety and calming effects.

    The Endocannabinoid System and Autism

    The Endocannabinoid system is where the CBD and autism connection really starts to make sense. A lot of autism’s symptoms are directly related to the functions of the body’s endocannabinoid system (ECS). The ECS is the largest regulatory system in the body and controls:

    • mood
    • pain
    • sleep
    • appetite
    • pleasure and reward
    • motor control
    • memory

    Plus, our bodies have endocannabinoid receptors in almost every cell. When a 2013 study found dysfunctions in cannabinoid receptors on immune cells in autistic children, it was an “aha” moment for CBD and autism researchers. Could supplementing autistic people with cannabis improve their symptoms?

    CBD and Autism

    Some parents, like Shifra Klein, would say yes. Her 12-year-old son was diagnosed with severe autism at age two and has been on over 13 medications to help control symptoms since.

    “Our son is almost completely weaned off of drugs [since beginning CBD treatment],” says Klein. “He is more focused in school, able to stay on task, understand and follow classroom multi-step directions, complete schoolwork, and is no longer at a ‘plateau’ and able to grasp new concepts. His eye contact is better, his language is more thought-out and he is able to create meaningful sentences and his annunciation is clearer. He also seems happier, in general.”

    CBD and autism have been a great fit for Klein’s son, but because there is practically no clinical evidence for its success, autism isn’t a qualifying condition for medical marijuana in most states. However, the anecdotal evidence is growing and has sparked the formation of activist groups like Mothers Advocating Medical Marijuana for Autism (MAMMA).

    Klein is an early education teacher as well as parent and so she understands the doubt, fear, and stigma parents experience when considering CBD and autism.

    “I still encourage other parents to use resources available to them, such as therapies, but this is such a wonderful addition and has really been effective for us,” says Klein.

    As far as dosing CBD goes, Klein warns it might be a bit of trial and error, but it will be well worth it. She also urges parents to make sure their CBD oil is from a reliable source and is tested by a third-party lab to ensure quality and safety.

    “I would never recommend anything to another child that I would not give to my own,” says Klein. “You will not harm your child by trying CBD to see if it works for them. You will not overmedicate your child with CBD.”

    The Problem with Other Medications

    CBD and autism come as a relief for parents because other drugs prescribed to children with autism are powerful. Often these kids are prescribed Abilify or Seroquel: anti-psychotics not specifically for autism, or children for that matter.

    “You won’t find even one single study that shows what happens to a very young child who’s treated lifelong with antipsychotics,” says Abigail Dar, mother of an autistic son, researcher, and advocate for cannabis for autism in Israel. “None of them [antipsychotic medications] have been targeted for children. I’m talking five [years old].”

    These antipsychotic drugs have tons of negative side effects, including dizziness, drowsiness, stomach pain, and weight gain. And yet, they are most doctor’s first choice for treating autism. However, many criticize them for being too strong and turning kids with social disabilities into zombies. Or, as Dar puts it: “You give it to children who can’t communicate how they feel.”

    Dar also pointed out another troubling dilemma with antipsychotic medications. One of their side effects includes lowering the seizure threshold, yet autistic children are at high risk for epilepsy; 30% of those with autism also have epilepsy. Dar’s son didn’t have epilepsy until he was 16 and she isn’t sure if it was caused by medications for the autism rather than the autism itself.

    “If he didn’t have epilepsy we may have triggered it,” says Dar. “I’m asking now, why did you give my son who’s already at risk for seizures [these drugs]?”

    Cannabis, on the other hand, is anecdotally more effective at treating symptoms and much less harmful. In fact, CBD oil without THC is non-psychoactive and has no side effects aside from possible drowsiness. CBD and autism is such a great match because children are more engaged whereas anti-psychotics leave them the opposite. Plus, hemp-derived CBD oil is available in all 50 states.

    CBD and autism have tons of potential. The anecdotal evidence is building and soon, we’ll have scientific evidence to back it up. For families looking for alternative treatment, CBD and autism might be the answer they were searching for.

    Reference Click Here

  • Everything You Need To Know About Using CBD

    Everything You Need To Know About Using CBD


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    The compound, found in the cannabis plant, is thought to be good for muscle pain, headaches and anxiety, among other things. But what does the research say?

    James Joliat, a 35-year-old video producer in Denver, has long experienced muscle and joint pain—mostly related to sports injuries. He says he started looking at natural remedies as an alternative to the prescription patches and pills his doctor recommended. After experimenting with homemade rubs infused with plant compounds—stuff like arnica and turmeric—he eventually stumbled onto topical cannabidiol (CBD) rubs.

    “I put that on my ankle after hiking or on my lower back, and it just feels like it really penetrates and has good anti-inflammatory properties,” he says. “I also fucked up my shoulder, and I felt like it helped a lot with the pain.”

    He’s been using topical CBD for years with good results, and he recently tried ingesting CBD oil, which he called an “amazing” experience. “I just felt super relaxed—kind of an anti-anxiety type of feeling,” he says. “My body felt super mellow and limber, but not in a tired kind of way.”

    “I just felt good,” he adds. “But I wasn’t high at all.” Joliat’s anecdotal experience with CBD is a common one. Some informal polling suggests a lot of people today are at least vaguely familiar with cannabidiol and have either used it themselves or know someone who has. But even some people who use it don’t seem to know exactly what it is or whether there’s any hard science out there to back up its benefits.

    What Is CBD?

    “Cannabidiol is a compound found in the cannabis plant,” says Jerzy Szaflarski, a professor of neurology and director of the Division of Epilepsy at the University of Alabama, Birmingham.

    Szaflarski explains that cannabis contains about 500 different compounds, some of which—including CBD and THC—interact with certain chemical receptors in the human nervous system. But unlike THC, CBD isn’t psychoactive—meaning it doesn’t cause any kind of a high. Despite that, the US Drug Enforcement Agency classifies CBD (and other cannabis compounds) as schedule I substances, making their sale illegal in many states.

    “The brain has these receptors that respond to endocannabinoids, which are neurotransmitters that are naturally produced in the body and brain,” says Jerald Simmons, a neurologist at Houston’s Comprehensive Sleep Medicine Associates. “Some of the cannabinoids in the marijuana plant are very similar to the endocannabinoids in the brain, and they act on the same receptors.”

    The nervous system’s endocannabinoid system is not well understood. But it’s thought to play a role in regulating pain, sleep, mood, memory, appetite, and other cognitive and physical processes. Because CBD is able to mimic the actions of some natural brain chemicals, its potential therapeutic benefits are wide-ranging but—at this point—nebulous. “We know that cannabidiol modulates the endocannabinoid system, but we don’t know how it works,” Szaflarski says. That said, there are theories.

    “THC”—the more-famous, high-inducing compound in cannabis—“works directly on the cannabinoid system, meaning it attaches to receptors and mimics some of our own internal endocannabinoids,” says Igor Grant, a professor and chair of psychiatry at the University of California, San Diego School of Medicine. But CBD’s interaction with the endocannabinoid system is subtler. “Normally, these endocannabinoid-signaling molecules are broken down by enzymes, and one thing CBD does is interfere with the actions of those enzymes.”

    Grant says this may lead to a “dampening” or mellowing of some neurochemical processes, including those linked to pain. “CBD may also react with other receptors, like those for serotonin, and it may have actions that reduce the inflammatory molecules produced whenever there is tissue damage or bacteria coming in,” he says. “But we really don’t know the mechanisms.”

    Should I take CBD to treat pain?

    Talk to people or spend time on internet message boards, and you’ll see CBD is thought to have anti-pain, anti-soreness, and anti-inflammatory benefits. Some rat studies have linked topical CBD treatments to a drop in arthritis-related pain and swelling, and more research suggests it could help relieve headaches.

    That headache study cites research linking CBD to lower rates of anxiety. (Since anxiety often produces headaches, the authors say, CBD could be a plausible headache remedy if those anti-anxiety benefits are legit.) Grant says he’s looked at the literature on CBD and anxiety, and some of it is enticing. He mentions a Brazilian study, for instance, that found people with a fear of public speaking felt less anxiety and less discomfort about their phobia after taking CBD, compared to those who took a placebo.

    “There’s also some evidence it reduces psychotic symptoms in people with schizophrenia and psychotic disorders,” Grant says. “But there are a lot of open questions at this point.”

    One area where CBD is clearly helpful: the treatment of seizures associated with one form of epilepsy. A 2017 New England Journal of Medicine study found ingesting oral CBD dramatically cut down most patients’ seizure frequency—a finding that prompted the FDA to support the approval of one CBD drug for use in the treatment of some epilepsy patients.

    How do people take CBD?

    It’s usually sold as a droplet-administered oil or a balm, but it’s also sold in caplets, under-the-tongue tabs, lotions, face serums, and other products.

    Some users speculate about appropriate dosages or methods of application—including whether or not a small amount of THC boosts CBD’s effects, or whether different methods of administration lead to quicker or more significant effects. Some CBD producers also claim that it has a cumulative effect, and so needs to be used regularly to produce a benefit. But Grant says it’s tough to say at this point exactly how people should (or shouldn’t) be using CBD.

    “Even where marijuana is legal, you often don’t know exactly what you’re getting,” he says. “I’m sure some of these [CBD] producers have labs and do correct labelling, but none of it’s secure like it is with pharmaceuticals.”

    The nutrition and supplement industry—which includes CBD products—is almost wholly unregulated. “The concentrations in products are only approximate, and I don’t know how well they’re tracked,” Szaflarski says. Even if you could absolutely trust a product’s label—and many CBD manufacturers, aware of the current scrutiny on their industry, go to great lengths to assure consumers of the quality of their products—there aren’t a lot of concrete facts when it comes to the type or amount of CBD a person should take for a specific ailment or aim.

    Are there any risks to taking CBD?

    Some studies have turned up evidence—nearly all of it from lab work or animal research—that CBD could potentially affect cell health, fertility, and the breakdown and metabolism of drugs in the liver. “There may be some interactions with pharmaceutical drugs,” Szaflarski says, mentioning drowsiness as one (but not the only) possibility.

    In human studies, including one that found anti-seizure benefits among epileptics, some people have reported diarrhoea, vomiting, fever, and fatigue while taking CBD.

    “But so far, the main risks are that it does seem to have a sedative action, so people could get drowsy,” Grant says. “I have not read about major side effects or bad reactions, so it seems relatively safe as far as we know, but we need systematic research on this.”

    While there are more unknowns than knowns at this point, Grant says he doesn’t discount all the anecdotal CBD reports. “You hear somebody say, ‘Hey, I gave this to myself and my kid and we feel a lot better,’ and we should never dismiss that kind of information,” he says. He points out that many modern medicines were discovered when researchers followed up on exactly this sort of human trial-and-error evidence. “But we still need to do the studies that confirm whether all the good things are true, and how much to give, and how to give it,” he says. “These are all questions that need to be answered.”

    Reference: Vice


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