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treatment

Tag: treatment

CT Scan – Tumour Shrinks After Taking CBD Oil
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Striking CT scan shows how ‘lung cancer patient’s tumours SHRANK within three months of him taking daily drops of cannabis-derived oil’

The 81-year-old, who hasn’t been identified, repeatedly refused chemotherapy

Instead, the ex-smoker opted to take CBD oil for two months to tackle his cancer

Doctors have now published stunning pictures showing how it helped him

The tale has been published in a medical journal by doctors in Stoke-on-Trent

A cancer patient who accepted the disease would kill him saw his tumours shrink – by taking drops of cannabidiol (CBD) oil each day.

The 81-year-old, who hasn’t been identified, repeatedly refused chemotherapy and other treatments to prolong his life.

Instead, the ex-smoker, believed to be from the Stoke-on-Trent area, opted to take CBD oil for three months to tackle his lung cancer.

Doctors have now published stunning scans, showing how doing so halved the size of his tumours and reversed the progression of his disease.

The tale has been published in a medical journal, where doctors claimed ‘CBD may have had a role in the striking response’.

However, experts have warned this is just one case. Claims that cannabis or any of its derived compounds could have any helpful impact on cancer are unproven.
The 81-year-old, who hasn’t been identified, repeatedly refused chemotherapy and other treatments to prolong his life (pictured a CT scan of the man’s tumours in July 2017)

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Instead, the ex-smoker, believed to be from the Stoke-on-Trent area, opted to take CBD oil for two months to tackle his lung cancer (pictured, a scan of his cancer in November 2017)

CBD – which doesn’t cause a ‘high’ – is an extract of the cannabis plant. It is legal in the UK and can be sold on the high street.

The anti-inflammatory compound is already backed for its plethora of benefits by the World Health Organization.

However, the latest case report offers hope it could tackle certain forms of cancer, as well as combating pain, epilepsy and anxiety.

Doctors at the Royal Stoke University Hospital treated the patient, who already survived a shave with prostate cancer 15 years ago.

They pointed to an array of promising research which has suggested CBD may have the power to slow the growth of some tumours.

Scientists believe CBD produces oxygenated chemicals in the body which may cause cancerous cells to kill themselves.

Though, several other pathways have also been suggested – including stopping the tumour from recruiting cells that help them grow.

Ian Hamilton, a drug researcher at the University of York, who did not treat the patient, told MailOnline the case report was ‘important’.

He said: ‘This single case study adds to several that offer some promise in the use of CBD products in the treatment of cancer.

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The tale has been published in a medical journal, where doctors claimed ‘CBD may have had a role in the striking response’ (pictured, a scan of his cancer in July 2017)

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But, in a bizarre twist of events, a CT scan in November 2017 (pictured) revealed the ‘near total resolution’ of the mass to just 1.3 by 0.6cm

‘I think there is real potential with CBD but there is also a lot of false hope being given. This kind of case study is important but is unlikely to change medical practice.

‘It will need a larger randomised control trial, which would help distinguish how much is down to the placebo effect.’

The patient had already been diagnosed with chronic obstructive pulmonary disease (COPD) – a debilitating lung condition that causes breathlessness.

As well as having COPD, he also used to smoke around 20 cigarettes a day when he was in his 20s and 30s. Both are risk factors for lung cancer.

The man was diagnosed with lung adenocarcinoma in October 2016, after going to his GP complaining that his breathlessness was getting worse.

Scans showed a shadow in his left lung, which turned out to be a 2.5 by 2.5cm cancerous tumour. The disease had also spread to his lymph nodes.

Lung adenocarcinoma is a form of non-small cell lung cancer, accounting for around 80 per cent of cases in the UK.

Around 44,500 people are diagnosed with lung cancer as a whole every year in the UK. The figure is around 260,000 in the US.

Only 15 per cent of patients with an adenocarcinoma of the lung survive for five years, according to statistics.

Doctors at Royal Stoke University Hospital then offered him chemotherapy and radiotherapy in the hope of prolonging his life.

However, he declined treatment because of his age as he did not want to suffer adverse side effects in the final years of his life.

A CT scan conducted at the hospital in December 2016 revealed the lung mass had increased in size, measuring 2.7 × 2.8 cm.

He was once again offered treatment – but declined, lead author Dr Josep Sulé-Suso wrote in SAGE Open Medical Case Reports.

Another chest X-ray in July 2017 showed his disease was slowly progressing.

But, in a bizarre twist of events, a CT scan in November revealed the ‘near-total resolution’ of the mass to just 1.3 by 0.6cm.

Dr Sulé-Suso and colleagues also spotted a ‘significant reduction’ in the size and number of mediastinal lymph nodes.

Doctors then asked the patient about his lifestyle, in order to understand what may have prompted the dramatic effect on his cancer.

He revealed he had started taking CBD oil in September – just two months before the scan showed his tumour had halved in size.

At first, he consumed two drops twice daily for a week, before bolstering his dose to nine drops twice a day until the end of September.

The patient gave up taking the oil a week after his positive CT scan in November because he ‘didn’t like the taste and felt sick’.

No other changes in diet, medication or lifestyle were noted, leading the medics to believe CBD oil was the key driver in the shrinking tumour.

Dr Sulé-Suso and colleagues did not reveal the man’s condition now, or if he ever started taking CBD oil again.

The oil he was taking contained 200mg of CBD in every 10ml.

https://www.dailymail.co.uk/embed/video/1794588.html

Reference: Dailymail
April 5, 2020
Ever Thought About Supplementing Your Pet’s Diet With CBD

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Over the last several years, CBD has increasingly been shown to aid in the treatment of seizures. The evidence is so strong that the FDA, an organization notoriously opposed to cannabis, approved the first CBD-based medication for one particular seizure disorder at the end of June.

Multiple studies have shown CBD is effective in treating these ailments in humans, but a small pilot study conducted in Colorado has also suggested it may be useful in helping ease tremors in dogs. Researchers at Colorado State University, Fort Collins conducted a study of 16 dogs that suffer from seizures and found 90 percent of those given CBD oil experienced a reduction in seizures versus 20 percent that were given placebo treatment.

This is not the first time veterinary researchers have investigated the potential health benefits of CBD for dogs. Last year, researchers at the Fort Collins veterinary school sought to determine the effects of the non-psychoactive cannabinoid on arthritis. Other researchers at Auburn University’s College of Veterinary Medicine and the veterinary school at the University of Pennsylvania have also attempted to study the effects of CBD on dogs, but Dawn Booth of Auburn University’s veterinary school was forced to wait for federal approval. Researchers as the University of Pennsylvania halted their study after the DEA declared CBD is still considered part of cannabis’ Schedule I designation.

In the meantime, the American Veterinary Medical Association has expressed its desire for the DEA to reclassify CBD. “The concern our membership has worries about people extrapolating their own dosages, looking to medicate their pets outside the realm of the medical professional,” Board Chairman Michael Whitehair said last year. “This is an important reason for us to continue the research.”’

CBD products for pets have gained popularity in the years since legalization has become the norm in states around the country, but there is still limited research on its benefits because of federal laws, which has also hindered research into the use of cannabis for human consumption.

The small study at Colorado State University shows promise but requires a larger scale. “Although really exciting results, it still has to be taken with a little bit of a grain of salt, because the power of the study is diminished when you don’t have a lot of dogs involved,” said Dr Stephanie McGrath, a veterinary neurologist who led the study, while discussing her findings at a press conference on Monday. “Unfortunately, epilepsy is a fairly common condition in dogs,” she said, noting that there are currently very few options to treat it.

Though the pilot study was small and requires further research, more in-depth study into the effects of CBD on dogs may open a door for improved care for them, just as it has for humans suffering from similar ailments.

Referece:theantimedia.com

September 5, 2019
What’s The Difference Between Non-Intoxicating CBD & THC

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Why is THC intoxicating and CBD is not? How can one cannabinoid alter the mind, & the other not at all?

When we’re talking about cannabis and euphoria, we’re dealing exclusively with CB1 receptors, which are concentrated in the brain and the central nervous system. The difference between CBD vs. THC comes down to a basic difference in how each one interacts with the cannabinoid 1 (CB1) receptor. THC binds well with CB1 cannabinoid receptors. CBD has a low binding affinity for CB1 receptors. That’s where the two diverge.

Think of it like an electrical plug connecting to a wall socket. A THC molecule is perfectly shaped to connect with CB1 receptors. When that connection happens, THC activates or stimulates those CB1 receptors. Researchers call THC a CB1 receptor agonist, which means THC works to activate those CB1 receptors.

THC partially mimics a naturally produced neurotransmitter known as anandamide, aka “the bliss molecule.” Anandamide is an endocannabinoid which activates CB1 receptors. Animal studies have taught us that anandamide can increase appetite and enhance pleasure associated with food consumption, and it’s likely responsible for some of the rewarding effects of exercise (e.g. the “runner’s high”). Anandamide also plays a role in memory, motivation, and pain. THC is a “key” that so closely resembles anandamide that it activates CB1 receptors, allowing it to produce some of those same blissful feelings.

CBD, by contrast, is not a good fit with CB1 receptors. It’s categorized as an antagonist of CB1 agonists. This means that it doesn’t act directly to activate or suppress CB1 receptors—rather, it acts to suppress the CB1-activating qualities of a cannabinoid like THC. In other words, when you ingest THC and CBD, the THC directly stimulates those CB1 receptors, while the CBD acts as a kind of modulating influence on the THC. As Project CBD co-founder Martin Lee once wrote: “CBD opposes the action of THC at the CB1 receptor, thereby muting the psychoactive effects of THC.”

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Left: THC directly stimulates the CB1 receptor. This interaction underlies the major psychoactive effects of Cannabis consumption. Right: CBD reduces, or “antagonizes,” THC’s ability to stimulate CB1 receptors. This can decrease some of THC’s effects, especially negative effects like anxiety and short-term memory impairment.

How does that work in real life? Let’s say you vaporize cannabis flower with 24 percent THC. If that flower has 0.2 percent CBD, the THC is going to excite your CB1 receptors with almost no interference from CBD. You may feel extremely high, and you might also experience some of the less desirable effects of THC, such as a heightened feeling of paranoia. If you consume cannabis with 24 percent THC and 6 percent CBD, though, the CBD should have a dampening effect on the THC. You’ll still feel high, but perhaps not stupefyingly so—and the CBD should help keep the paranoia in check.

This difference has had profound political implications. As the founders of Project CBD have noted, some have mistakenly labelled THC the “bad cannabinoid” and CBD the “good cannabinoid.” Legislators have passed many “CBD-only” laws in Southern states in an effort to allow patients access to this potent cannabinoid while prohibiting its euphoric sibling. But the pioneering cannabis researcher Raphael Mechoulam has often spoken of the “entourage effect,” the idea that cannabinoids and terpenes may work better together than in isolation. The GW Pharma product Sativex, for example, is a drug approved outside the U.S. for treatment of MS-related muscle spasticity. Sativex contains with a nearly 1:1 CBD-to-THC ratio.

As researchers learn more about CBD and the role of other cannabinoids and compounds in the treatment of conditions like MS, we may be able to more accurately dose CBD in combination with other cannabis-derived compounds.

Reference: Leafly

August 5, 2019
Herb Spoke To Parents Treating Their Children With CBD
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Autism spectrum disorder affects one in 68 American children, but what’s the relationship between CBD and autism? Parents treating children with CBD?

Although there are currently no published studies on the subject, there is tons of anecdotal evidence that says CBD and autism is a good fit, especially considering how strong the prescription alternative can be. We did the research and spoke with mothers of children with autism, to teach you how CBD and whole plant medicine can be an effective treatment for autism.

What is Autism?

Autism is a developmental disorder that affects people’s ability to communicate and interact with others. It is known as a spectrum because it affects individuals in varying degrees. Some other behaviours that are common in autism spectrum disorder include delayed language, difficulty making eye contact and having a conversation, sensory sensitivities, intense interests, and repetitive behaviour. Because it’s a spectrum, folks with autism may display many or few of these signs – it depends on the individual.

Autism is frequently accompanied by other medical issues, like gastrointestinal (GI) disorder, sleep disturbances, anxiety, phobias, ADHD, and OCD. But that’s the first place where CBD and autism link, many of those medical issues can be relieved by cannabis.

What’s more, the inability to communicate can be very frustrating for those with autism. It can cause lead to other behaviours, like anxiety, rage, and self-harm, as well as body rocking and other repetitive self-soothing behaviours. But this is where CBD and autism meet again, because of cannabis’ anti-anxiety and calming effects.

The Endocannabinoid System and Autism
The Endocannabinoid system is where the CBD and autism connection really starts to make sense. A lot of autism’s symptoms are directly related to the functions of the body’s endocannabinoid system (ECS). The ECS is the largest regulatory system in the body and controls:

mood

pain

sleep

appetite

pleasure and reward

motor control

memory

Plus, our bodies have endocannabinoid receptors in almost every cell. When a 2013 study found dysfunctions in cannabinoid receptors on immune cells in autistic children, it was an “aha” moment for CBD and autism researchers. Could supplementing autistic people with cannabis improve their symptoms?
CBD and Autism

Some parents, like Shifra Klein, would say yes. Her 12-year-old son was diagnosed with severe autism at age two and has been on over 13 medications to help control symptoms since.

“Our son is almost completely weaned off of drugs [since beginning CBD treatment],” says Klein. “He is more focused in school, able to stay on task, understand and follow classroom multi-step directions, complete schoolwork, and is no longer at a ‘plateau’ and able to grasp new concepts. His eye contact is better, his language is more thought-out and he is able to create meaningful sentences and his annunciation is clearer. He also seems happier, in general.”

CBD and autism have been a great fit for Klein’s son, but because there is practically no clinical evidence for its success, autism isn’t a qualifying condition for medical marijuana in most states. However, the anecdotal evidence is growing and has sparked the formation of activist groups like Mothers Advocating Medical Marijuana for Autism (MAMMA).

Klein is an early education teacher as well as parent and so she understands the doubt, fear, and stigma parents experience when considering CBD and autism.

“I still encourage other parents to use resources available to them, such as therapies, but this is such a wonderful addition and has really been effective for us,” says Klein.

As far as dosing CBD goes, Klein warns it might be a bit of trial and error, but it will be well worth it. She also urges parents to make sure their CBD oil is from a reliable source and is tested by a third-party lab to ensure quality and safety.

“I would never recommend anything to another child that I would not give to my own,” says Klein. “You will not harm your child by trying CBD to see if it works for them. You will not overmedicate your child with CBD.”

The Problem with Other Medications

CBD and autism come as a relief for parents because other drugs prescribed to children with autism are powerful. Often these kids are prescribed Abilify or Seroquel: anti-psychotics not specifically for autism, or children for that matter.

“You won’t find even one single study that shows what happens to a very young child who’s treated lifelong with antipsychotics,” says Abigail Dar, mother of an autistic son, researcher, and advocate for cannabis for autism in Israel. “None of them [antipsychotic medications] have been targeted for children. I’m talking five [years old].”

These antipsychotic drugs have tons of negative side effects, including dizziness, drowsiness, stomach pain, and weight gain. And yet, they are most doctor’s first choice for treating autism. However, many criticize them for being too strong and turning kids with social disabilities into zombies. Or, as Dar puts it: “You give it to children who can’t communicate how they feel.”

Dar also pointed out another troubling dilemma with antipsychotic medications. One of their side effects includes lowering the seizure threshold, yet autistic children are at high risk for epilepsy; 30% of those with autism also have epilepsy. Dar’s son didn’t have epilepsy until he was 16 and she isn’t sure if it was caused by medications for the autism rather than the autism itself.

“If he didn’t have epilepsy we may have triggered it,” says Dar. “I’m asking now, why did you give my son who’s already at risk for seizures [these drugs]?”

Cannabis, on the other hand, is anecdotally more effective at treating symptoms and much less harmful. In fact, CBD oil without THC is non-psychoactive and has no side effects aside from possible drowsiness. CBD and autism is such a great match because children are more engaged whereas anti-psychotics leave them the opposite. Plus, hemp-derived CBD oil is available in all 50 states.

CBD and autism have tons of potential. The anecdotal evidence is building and soon, we’ll have scientific evidence to back it up. For families looking for alternative treatment, CBD and autism might be the answer they were searching for.

Reference Click Here
June 5, 2019

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